#53 The retro synthetic approach for this molecule

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Question

#53 The retro synthetic approach for this molecule

The retro synthetic approach for this molecule

Answer

Step 1

The molecule is as follows:

The retro synthetic approach for this molecule

Step 2

The retro synthetic approach for this molecule is shown below.

The retro synthetic approach for this molecule

Step 3

Therefore, the preparation of this molecule can be achieved by the following steps:

Step1: First there is Diels alder reaction takes place between 1,3-butadiene and bromoethene.

The retro synthetic approach for this molecule

Step 4

Step2: The resultant product is treated with magnesium in dry ether condition to form aryl Grignard reagent.

The retro synthetic approach for this molecule

Step 5

Step3: Then this aryl Grignard reagent react with butanone and formed product and again this product react with water to formed final product as shown:

The retro synthetic approach for this molecule